Flavorful Crock Pot Turkey Tenderloin

This crock pot turkey tenderloin is a weeknight dinner lifesaver. The slow cooker transforms lean turkey tenderloin into a juicy, tender main dish that’s full of flavor from a simple blend of herbs and spices. It’s a healthy, hands-off recipe that comes together with minimal effort, making it perfect for busy families. Whether you serve it with mashed potatoes and stuffing for a holiday-worthy meal or pair it with veggies and rice for a lighter dinner, this turkey tenderloin recipe is as versatile as it is delicious.

Why This Is The Best Crock Pot Turkey Tenderloin Recipe

If you love turkey and want a dish that takes it to a whole new level, then my crock pot turkey tenderloin recipe is the dish for you!

Not only is this a simple recipe, but it is also one of the most delicious turkey recipes I have ever tried. With its juicy white meat and flavorful poultry seasoning, it makes the perfect meal for a small get-together or family dinner.

I love turkey because it's such a lean meat, and slow cooking it makes for a super healthy recipe. Not only that, but it's also really versatile. I like to serve my turkey tenderloins with class holiday sides like cranberry sauce and these cheesy mashed potatoes, but you can also serve it with a salad, some baked potatoes, or really any of your other favorite side dishes.

Why You'll Love This Turkey Tenderloin Recipe

• It’s easy and hands-off: Everything cooks right in the slow cooker, which means minimal prep and virtually no cleanup. Just season the turkey tenderloin, set it in the crock pot, and let it do the work for you.
• A healthy dinner option: This recipe is made with lean turkey tenderloin and simple seasonings—no heavy sauces or extras—so it’s naturally high in protein, low in fat, and carb-friendly. It’s a nutritious main dish you can feel good about serving any night of the week.
• Perfect for Thanksgiving (or any holiday): If roasting a whole turkey feels intimidating or too much work, this crock pot version is a fantastic alternative. I’ve made it for Thanksgiving, and my family loved it just as much as the traditional bird. It’s tender, juicy, and still feels festive—without the stress.
• Versatile for meals beyond the holidays: Turkey tenderloin isn’t just for Thanksgiving. This recipe works just as well for Sunday dinners, meal prep, or busy weeknights. Pair it with mashed potatoes, roasted veggies, or even slice it up for sandwiches the next day.

Ingredients

• 12 oz. Turkey tenderloin- you can use two large tenderloins for extra guests.
• ¾ cup Chicken broth- to keep the meat nice and juicy.
• ½ tbsp. Italian seasoning- for a depth of flavor.
• ½ tsp. Onion powder and garlic powder- to add more savory flavors.
• Salt and pepper to taste
• 1 tbsp. Butter- this is my secret ingredient that makes the meat so tender and delicious.

How To Make Crockpot Turkey Tenderloin

Step 1: Prep

Add the chicken broth to the crock pot along with the Italian herbs, onion powder, garlic powder, salt, and pepper. Add the turkey to the crock pot and flip it so each side is coated with broth and spices.

Step 2: Cook the Turkey Tenderloin

Add the butter on top of the turkey and place the lid on the crock pot. Cook on high for 2-3 hours or low for 4-6 hours.

Step 3: Serve

 Remove the meat and let it rest for 5 minutes before slicing. Serve warm with mashed potatoes or any sides you want. Enjoy!

My Pro Tips To Make The Best Turkey Tenderloin

• Pat the turkey dry before seasoning: Make sure to dry the turkey tenderloin completely with paper towels before adding seasonings. Removing excess moisture helps the spices stick better and ensures the outside develops a nice golden finish instead of steaming in the slow cooker.
• Try it with different proteins: While turkey tenderloin is lean and flavorful, this recipe works beautifully with pork tenderloin or even chicken tenderloins. Just adjust the cook time slightly since chicken tends to cook faster. It’s a versatile method you can use year-round.
• Layer in extra flavor: This recipe is delicious as-is, but you can easily customize it. A splash of soy sauce adds umami, olive oil keeps the meat extra moist, brown sugar balances the savory notes with a touch of sweetness, kosher salt enhances flavor, and chili powder adds gentle heat. Mix and match to create your perfect flavor profile.
• Don’t overcook: Every slow cooker runs a little differently, so start checking the turkey around the 3-hour mark. Turkey tenderloin is done when it reaches 165°F internally. Using a meat thermometer is the best way to ensure it stays juicy and never dries out.
• Let it rest before slicing: After cooking, let the turkey rest for 5–10 minutes before slicing. This allows the juices to redistribute so every bite stays moist and flavorful.

How I Recommend Storing Leftovers

• In the fridge: Put any leftovers in an airtight container and store it for up to 4 days.
• In the freezer: Transfer the turkey to a freezer-safe container and freeze for up to 6 months.
• Reheating: My favorite way to reheat the meat is to add it to a skillet with a little broth and warm it over medium heat on both sides for 2 minutes.

Turkey Tenderloin FAQS

What can I serve with crock pot turkey tenderloin?

This turkey tenderloin pairs perfectly with classic comfort food sides like fluffy cathead biscuits, red skin mashed potatoes, and Pioneer Woman stuffing. For a lighter meal, try it with roasted vegetables, a fresh salad, or garlic green beans. Leftovers also make amazing sandwiches the next day.

Is turkey tenderloin the same as turkey breast?

Not exactly. Turkey tenderloin is a boneless, skinless cut located beneath the breast. It’s much smaller, leaner, and cooks more quickly than a whole turkey breast, which makes it perfect for weeknight dinners or smaller holiday gatherings.

How do I know when turkey tenderloin is fully cooked?

The best way to tell is by using a meat thermometer. Turkey tenderloin is done when the thickest part reaches an internal temperature of 165°F. Cooking beyond this can dry it out, so check toward the end of the cooking time to keep it juicy and tender.

Can I make this turkey tenderloin ahead of time?

Yes. You can cook it fully, then store it in an airtight container in the fridge for up to 3–4 days. To serve, reheat gently in the oven or slow cooker with a splash of broth to keep it moist.

Thanksgiving Recipes To Try Next

• Sweet potato cobbler
• Meatloaf with stuffing
• Ocean Spray cranberry sauce
• Candied yams
• Sweet potato pecan pie